YEAR: 2021

35. *Saini V, Kalra P, Sharma M,  Rai C, Saini Vikas, Gautam K, Bhattacharya S, Mani S, Saini K, Kumar S (2021). A cold chain independent specimen collection and transport medium improves diagnostic sensitivity, and minimizes biosafety challenges Covid19 molecular diagnosis. Microbiology Spectrum. 9, e01108-21 (2021) Doi: 10.1128/Spectrum.01108-21.               $Patent filed.

Research Highlight in Nature India: Microbial transport medium improves COVID-19 diagnostic. https://www.nature.com/articles/d44151-022-00003-x

​

34. Kumar P, Saini K, *Saini V, Mitchell T (2021). Oxalate Suppresses macrophage immunometabolism and anti-bacterial response to uropathogenic E. coli (UPEC) infection. Frontiers in Immunology.  Vol 12, Article 694865. 

​

33  FNU Kirandeep, Kumar A, Sharma A, Sahoo SC, Zangrando E, Saini V, Kataria R, Mehta S K. Metal organic framework as “Turn-On” fluorescent sensor for Zr (IV) ions and selective   adsorbent for organic dyes. Micro Chemical Journal. https://doi.org/10.1016/j.microc.2021.106824 (online Sept 13, 2021). 

​

32. Richa FNU, Kushwaha N, Negi S, Kataria R, and Saini V* (2021). Synthesis, characterization and utility   of a series of novel solvated copper (II) complexes as surface disinfectant against hospital acquired infections. Dalton Transactions. DOI: 10.1039/D1DT00199J. [Back cover page]* Patent filed.
 
31. Kunota TTR, Rahman MA, Truebody BE, Mackenzie JS, Saini V, Lamprecht DA, et al. Mycobacterium tuberculosis H2S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility. Antioxidants. 2021; 10(8):1285.
 
30.   Gautam K, Negi S and Saini V* (2021). Targeting endogenous gaseous signaling molecules as novel Host-directed therapies against tuberculosis infection.Free Radical Research. Page 1-16, DOI: 10.1080/10715762.2021.1892091 
 
29.   Kapoor P, Chowdhury A; Kharbanda O.P.; Bablani D. P., Gautam K, and Saini V (2021).      Exploring Salivary Diagnostics in COVID-19: A Scoping Review and research suggestions. BDJ (British Dental Journal) Open. Vol. 7, Article number: 8. https://doi.org/10.1038/s41405-021-00064-7. 
 

YEAR: 2020
28.  Saini V* and Kalra P (2020).An illustrated step-by-step guide to establish a disinfection facility for reuse of personal protective equipment. Protocol Exchange. DOI:10.21203/rs.3.pex-1082/v1.
 
27.  Gupta P, Dutt V, Kaur N, Kalra P,  Gupta S,  Dua A, Dabur R, Saini V, and Mittal A (2020). S-allyl Cysteine: A Potential Compound against Skeletal Muscle Atrophy. BBA - General Subjects. https://doi.org/10.1016/j.bbagen.2020.129676. 
 
26.  Taneja V, Kalra P, Goel Manish, Khilnani GC, Saini V, Prasad GBKS, Gupta UD, and Prasad HKP (2020).Impact and Prognosis of the Expression of IFN-α Among Tuberculosis Patients. PLoS One. https://doi.org/10.1371/journal.pone.0235488. 
 
25.  Saini V*, Sikri K, Batra SD, Kalra P and Gautam K. (2020). Development of a highly effective low-cost vaporized hydrogen peroxide-based method for disinfection of personal protective equipment for their selective reuse during pandemics. Gut Pathogens. 12:29.

 
24. Saini V, Chinta K, Reddy VP, Stein A, Lamprecht DA, Glasgow JN, Bailey SM, Moellering DR, Lancaster J, Steyn AJC (2020). H2S stimulates Mycobacterium tuberculosis respiration and growth to exacerbate tuberculosis. Nature Communications. 11, 557, 1 -17. https://doi.org/10.1038/s41467-019-14132-y.
       
Highlighted in Nature Asia as Research Highlight: This noxious gas aggravates TB. https://www.natureasia.com/en/nindia/article/10.1038/nindia.2020.14.
 
23.  Vashishta D, Sharma S, Kumar R, Saini Vaneet, Saini V, Ibhadonc A, Sahoo SC, Sharma S, Mehta S K, Kataria R (2020).Dehydroacetic acid Derived Schiff base as Selective and Sensitive Colorimetric Chemosensor for the Detection of Cu(II) ions in Aqueous Medium. Micro Chemical Journal. Vol.155, June 2020, 104705. 

 

YEAR: 2019
22.  Chinta K, Rahman A, Saini V, Glasgow J, Reddy VP, ………………………………. Agarwal A, Steyn AJC (2019). Micro-anatomic distribution of myeloid Heme Oxygenase-1 protects against free radical-mediated immunopathology in human tuberculosis. Cell Reports, 25 (7), 1938-1952. e5.  (Cover page article).

21.   Gupta P, Kaur N, Saini V, Bala M, Sherawat S, Gupta S, Dua A, Kumar V, Dutt V, Injeti Elisha, Mittal A (2019). Cinnamaldehyde regulates H2O2-induced atrophy by ameliorating the proteolytic and antioxidant defense systems. J of Cellular Physiology. https://doi.org/10.1002/jcp.27348. 
 

YEAR: 2018

20.   Kumar S, Saini V, Maurya IK, Kumari M, Kataria R, Gupta GK, Kumar V (2018). Design, synthesis, DFT, docking studies and ADME prediction of some new coumarinyl linked pyrazolylthiazoles: Potential standalone or adjuvant antimicrobial agents. PLoS One. 13(4): e0196016. 
 

19.  Reddy VP, Chinta KC, Saini V, Glasgow JN, Hull T, Traylor A, Rey-Stolle F, Soares M, Barbas C, Nargan K, Naidoo T, Ramdial PK, George JF, Agarwal A, Steyn AJC (2018). Ferritin H deficiency in myeloid compartments dysregulates host energy metabolism and increases susceptibility to M. tuberculosis infection. Frontiers in Immunology. Vol.9, e 00860 (26 pages). 

​

18. Pacl T Hayden, Reddy VP, Saini V, Chinta K, and Steyn AJC (2018). Host-pathogen redox dynamics modulate Mycobacterium tuberculosis pathogenesis. Pathogens and Disease. fty036. 

17.   Dutt V, Saini V, Gupta P, Kaur N, Bala M, Gujar R, Grewal A, Gupta S, Dua A, Mittal A (2018). S-allyl cysteine inhibits TNF alpha induced skeletal muscle wasting through suppressing proteolysis and expression of inflammatory molecules. Biochim Biophys Acta. (Gen Subjects); Vol. 1862 (4): 895-906. 

16. Patel M, Yarlagadda V, Adedoyin O, Saini V, Oreoluwa D, Holmes R, Mitchell T (2018). Oxalate induces mitochondrial dysfunction and disrupts redox homeostasis in a human monocyte derived cell line. Redox Biology. Vol. 15, 207-215.   

​

YEAR: 2017
15. Cumming B, Rahman A, Lamprecht D, Rhode K, Saini V, Russell D, Steyn AJC (2017). Mycobacterium tuberculosis WhiB3 is a global metabolic regulator that modulates the host cell-cycle. PLoS Pathogens 13 (5), e1006389. 

14.  Talwar GP, Gupta JC, Mustafa AS, Zaheer SA, Choudhury, Kar HK, Katoch K, Katoch VM, Parida S, Reddy P, Ahmed N, Saini V, Gupta S (2017).  Development of a potent invigorator of immune responses endowed with both preventive and therapeutic properties. Biologics: Targets and Therapy (11), 55—63. 
 

YEAR: 2016
13.  Chinta K, Saini V, Glasgow J, Mazorodze J, Rahman A, Reddy D, Lancaster J, Steyn AJC (2016). The emerging role of gasotransmitters in the pathogenesis of tuberculosis (2016). Nitric Oxide. Vol. 59, 28-41.
 
12.   Saini V#, Cumming BM#, Guidry L, Lamprecht D, Adamson JH, Reddy VP, Chinta KC, Mazorodze J, Glasgow JN, Richard-Greenblatt M, Gomez-Velasco A, Bach H, Av-Gay Y, Eoh H, Rhee K, Steyn AJC (2016). Ergothioneine maintains redox and bioenergetic homeostasis essential for drug susceptibility and virulence of Mycobacterium tuberculosis. Cell Reports. Vol. 14, 1–14. 

​​

YEAR: 2014
11.  Cumming BM, Lamprecht D, Wells RM, Saini V, Mazorodze J, Steyn AJ (2014). The physiology and genetics of oxidative stress in mycobacteria. Microbial Spectrum. Vol. 2 (3),1-22. 

 

YEAR: 2012
10. Saini V, Raghuvanshi S, Ahmed N, Khurana JP, Hasnain SE, TyagiAkhilesh K, TyagiAnil K (2012).Massive gene acquisitions in Mycobacterium indicus pranii provide a perspective on mycobacterial evolution.Nucleic Acids Res. Vol. 40 (21) 10832-10850. 
 

Commentary at Nature: 'Mosaic genome' holds clue to TB, leprosy vaccines http://www.nature.com/nindia/2012/120921/full/nindia.2012.137.html
Vaccine news daily.com: Indian scientists use TB-related bacterium to boost TB vaccine
http://vaccinenewsdaily.com/stories/510533395-indian-scientists-use-tb-related-bacterium-to-boost-tb-vaccine

9.  Regev D, Surolia R, Karki S, Zolak J, Montes-Worboys A, Oliva O, Guroji P, Saini V, Steyn AJC, Agarwal A and Antony V (2012). Heme oxygenase-1 promotes granuloma development and protects against dissemination of mycobacteria. Laboratory Investigation. doi:10.1038/labinvest.2012.125. Vol. 92 1541-52. 

This study for the first time revealed the role of host gene HO1 in the formation of organized granuloma structures, a cardinal aspect of TB disease and virulence. This has led to follow up studies at NIH to evaluate HO-1 induction as a marker to distinguish different stages of clinical TB.
 
8.  Saini V, Farhana A, Glasgow JN, Steyn AJC (2012). Iron sulfur cluster proteins and microbial regulation: Implications for understanding tuberculosis. Current Opinion in Chemical Biology. Vol. 16 (1–2), 45–53. 
This is the first study profiling Fe-S cluster proteins in M. tuberculosis (Mtb) and analyzes how Fe-S cluster proteins make Mtb more amenable to an intracellular survival.

7.  Farhana A, Saini V, Kumar A, Lancaster J, Steyn AJC (2012). Environmental heme sensor proteins: Implications for understanding bacterial pathogenesis. Antioxidants and Redox signaling. Vol. 17 (9), 1232-1245. 

​

YEAR: 2011
6.  Kumar A, Farhana A, Guidry L, Saini V, Hondulas M, Steyn AJC (2011).  Redox homeostasis in mycobacteria: the key to tuberculosis control? Expert reviews in Molecular Medicine. Vol. (13): e39. DOI: 10.1017/S1462399411002079. (25 pages)

5.  Saini V, Farhana A, Steyn AJC (2011).  Mycobacterium tuberculosis WhiB3: A novel iron-sulfur cluster protein that regulates redox homeostasis and virulence. Antioxidants and Redox signaling. Vol 16 (7) 687-697. 

 

YEAR: 2009

4.   Saini V, Raghuvanshi S, Ahmed N, Talwar GP, Khurana JP, Hasnain SE, Tyagi Akhilesh K, Tyagi Anil K (2009). Polyphasic taxonomic analysis establishes Mycobacterium indicus pranii as a distinct species. PLoS ONE 4(7): e6263.doi: 10.1371/journal.pone. 0006263(10 pages).
This work established the unique species identity of M. indicus pranii leading to the deposition of cultures in international accredited repositories as a new species. Subsequent to this study, more than 55 papers have been published on this strain.

 

YEAR: 2008
3.  Talwar GP, Ahmed N, Saini V (2008). The use of the name Mycobacterium w for the leprosy immunotherapeutic bacillus creates confusion with M. tuberculosis-W (Beijing strain): A suggestion. Infect Genet Evol. Vol. 8(1), 100-101. 

​

YEAR: 2007
2. Ahmed N#, Saini V#, Raghuvanshi S, Khurana JP, TyagiAkhilesh K, TyagiAnil K, Hasnain SE (2007).Molecular analysis of a leprosy immunotherapeutic bacillus provides insights into Mycobacterium evolution. PLoS ONE 2(10): e968.doi:10.1371/journal.pone.0000968.). (8 pages). 

​

Commentary:-

1. Indian Bug Is the Ancestor of Crohn's Disease Pathogen http://www.sciencedaily.com/releases/2007/10/071002213435.htm)

2. Commentary at Nature: Indian bug great grandpa to Crohn's disease pathogen (http://www.nature.com/nindia/2007/071004/full/nindia.2007.24.html).

​

YEAR: 2004
1. Saini V, Berwal R, Sharma J, Singh A (2004).  Biofertilizers: Current Status and Perspectives in agriculture. Poll Res. vol. 23 (4): 665-76. 

​

PUBLISHED BOOK CHAPTERS:

1. Sharma J, Saini V, Singh A, Singh Narender (2005). Phyto-remediation of organic pollutants. In: Biotechnological Applications in Environmental Management Ed. by: R.K. Trivedi and Sadhana Sharma. BS Publishers, India ISBN: 81-7800-090-3.

​

2. Berwal R, Saini V, Sharma J, Gupta S (2005). Ribozyme Technology. For Advances in Biotechnology. Ed.  by Dr. P.C. Trivedi. Agrobios Publishers (India). 395-414.

​

3. Saini V, Berwal R, Sharma J, Singh A (2005).  Transgenic Plants: The Genetically Modified Food for Thought. For Advances in Biotechnology. Ed. by Dr. P.C. Trivedi. Agrobios Publishers (India). 83-97.

​

4. Steyn AJ, Mai D, Saini V, Farhana A (2012). Protein-protein interaction in the –omics era: Understanding Mycobacterium tuberculosis function. For Systems Biology of Tuberculosis. Ed. by Prof. John Joe McFadden. Springer Newyork (USA). 79 - 106.